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Viagra Helps Men With Heart Failure!


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#1 David_LivinginTalisay

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Posted 25 March 2012 - 4:12 PM

Ron Winkley who is a britsh friend of mine, and a Siesmologist, has been away in Burma (Myanmar) for over 4 months on a project there, but came back earlier this week having completed this stage of the project.

Anyway he managed to get home in time for his youndest daughter, Alyssa's, 9th Birthday Party.

Another Guest at this party was 'Marty the Jew from Cebu' as he calls himself, with his Family.

Marty was telling me his cardiologist has prescribed him Viagra for his heart condition.

Well I have a Heart condition as well and listned but did wonder if he was doing a wind up?

Now having Googles this, it does appear to be genuine!
  • http://circ.ahajourn...t/99/1/168.full
  • http://circ.ahajourn...8.full.pdf html
  • http://www.dailymail...ove-health.html
  • Viagra and pulmonary hypertension


    Science News





  • ... from universities, journals, and other research organizations



    Viagra Helps Men With Heart Failure


    ScienceDaily (Aug. 7, 2002) — DALLAS, Aug. 6 - Men with congestive heart failure and erectile dysfunction (ED) safely used sildenafil (Viagra) to improve sexual function in a study reported in today's rapid access issue of Circulation: Journal of the American Heart Association.

    The popular medication may even make patients more likely to take their heart failure drugs, says author Edimar Alcides Bocchi, M.D., associate professor and chief of the heart failure clinics at the Sao Paulo University Medical School in Brazil.

    "Heart failure patients may become noncompliant with their congestive heart failure (CHF) treatment if they feel it causes or aggravates their ED," Bocchi says. "However, our study suggests that treating the ED may make patients more motivated to take their medicines."

    Sildenafil caused no harmful effects and improved exercise performance during treadmill exercise tests in 23 men with CHF (average age 50) and a history of ED, says Bocchi.

    Sildenafil blocks the activity of the enzyme phosphodiesterase type 5 (PDE5), which is active in multiple tissues and cells. The effects of PDE5 inhibition include increased production of nitric oxide, which is associated with improved function of the heart and blood vessels.

    The cardiovascular effects of sildenafil have created some concern that the drug might be harmful in men with CHF. But there's not enough data on the safety or potential harm of sildenafil in CHF patients.

    Most of the men had moderate or severe heart failure, and each had been referred for treatment of ED. On separate days, the men underwent two exercise treadmill tests, which consisted of a six-minute walk and a maximal exercise test. About an hour before the first test, the men received either 50 milligrams of sildenafil or a placebo. On the second day, the men received the opposite treatment (sildenafil or placebo) before exercise.

    Those treated with sildenafil had significantly lower blood pressure and heart rate and improvement in measures of oxygen consumption and carbon dioxide production compared with those on placebo. Total exercise time also increased significantly. A separate evaluation showed that treatment with sildenafil was associated with higher scores on a questionnaire related to erectile function.

    "Frequently, CHF patients, and especially their wives, are afraid their spouses will have heart failure symptoms or even death during sexual activity," says Bocchi. "Our study shows that the benefits may outweigh harmful side effects of treatment with sildenafil. The successful treatment of ED in CHF could not only improve sexual relationships but overall quality and success of CHF treatment."


    Co-authors are Guilherme Guimarães, Ph.D.; Amilcar Mocelin, M.D.; Fernando Bacal, M.D.; Giovanni Bellotti, M.D.; and José Franchini Ramires, M.D.

  • Sildenafil - Wikipedia, the free encyclopedia

    en.wikipedia.org/wiki/SildenafilSildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a ... This, in turn, reduces the workload of the right ventricle of the heart and ... is already becoming an accepted treatment for this condition, in particular in ..... "Source: Roger Clemens, host of athletes pop Viagra to help onfield performance".

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#2 Davaoeno

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Posted 25 March 2012 - 4:22 PM

Men with congestive heart failure and erectile dysfunction (ED) safely used sildenafil (Viagra) to improve sexual function


did you actually read this article David ?? From your response i think not


Sildenafil caused no harmful effects and improved exercise performance during treadmill exercise tests - hello - you take viagara and get on a treadmill and your exercise performance increases !! ???? wow ! who would ever have thought that !

I think anyone who is on a treadmill will improve their exercise performance !! wheres Jimmy when we need him to make a video on how not to interpret a scientific finding !

#3 USMC-Retired

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Posted 25 March 2012 - 4:35 PM

Helps Men With Heart Failure


Most people with heart failure are dead are they not?

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#4 David_LivinginTalisay

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Posted 25 March 2012 - 5:05 PM

Most people with heart failure are dead are they not?



A heart attack occurs when blood flow to a part of your heart is blocked for a long enough time that part of the heart muscle is damaged or dies. Your doctor calls this a myocardial infarction


You only die if the Heart Attack is Serious and you did not take any life saving steps (a simple asparin can help), and did not get immidiate medical help.

I was confirmed as having had a Heart Attack, from the Tropin T Enzyme Test and was diagnosed with Triple Valve heart Disease. Good jub my Heat Attack/Failure was MILD as it was not untill the morning that I had an ECG and not until later that day I was admitted to Perpetual Succuor Hospital ICU after that Tropin T test result.

So you smart remark, was not very accurate for all Heart Attacks was it Tim, as I certainly did not die from my Heart Attack/Failure (as it was a mild one) that was nearly 4 years ago?

#5 RickyL

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Posted 25 March 2012 - 5:07 PM

Viagara is good for you!?

#6 For Real

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Posted 25 March 2012 - 5:07 PM

The thread title should read Viagra helps men achieve heart failure. Sildenafil was first trialled as a hypertension drug and failed.
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#7 For Real

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Posted 25 March 2012 - 5:13 PM

Viagra is good for you!?

Well it could be used to stop the old guys in the nursing home from rolling out of bed and breaking a hip, but that's about it.
If Private Percival will not stand to attention at the drill square without a walking frame then there is a clue there, you are simply taking risks partaking in intercourse. Some drugs assist length of life, many improve quality of life but this one improves the quality at a length of life cost.

Edited by Malipayon Puti, 25 March 2012 - 5:16 PM .


#8 CardiacKid

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Posted 25 March 2012 - 5:15 PM

Sildenafil is a vascular dilator. If you use it and have angina within 14 days that is treated with nitroglycerin your blood pressure will drop to zero and you will die. This was explained to me very clearly by my cardiologist in the U.S. If you do use Sildenafil you should have some means of notifying Emergency personnel of the date you last used it. This is one that should be discussed frankly with your cardiologist. Nitroglycerin sprays are often used to ease angina, and a form that is absorbed through the tissues under the tongue is widely prescribed.

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#9 CardiacKid

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Posted 25 March 2012 - 5:24 PM

Most people with heart failure are dead are they not?

Surviving congestive heart failure is common. This is when the sac around the heart fills with fluid and restricts the heart's ability to pump. I was hospitalized for pneumonia and it occurred. Fortunately my doctor recognized it and gave me a diuretic. Swollen feet and ankles in older people can be a sign of congestive heart failure. I now look upon it as just one more pothole in the road to growing old.

#10 David_LivinginTalisay

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Posted 25 March 2012 - 6:11 PM

Men with congestive heart failure and erectile dysfunction (ED) safely used sildenafil (Viagra) to improve sexual function

did you actually read this article David ?? From your response i think not

Sildenafil caused no harmful effects and improved exercise performance during treadmill exercise tests - hello - you take viagara and get on a treadmill and your exercise performance increases !! ???? wow ! who would ever have thought that !


Not sure why you trying to trivialise this Topic which is NOT a JOKE, but you seem intent on trying to make it one and for what reason I am not sure?

If you read that particular article in isolation and only saw part of the report, then this explians you very biased view.


Most of the men had moderate or severe heart failure, and each had been referred for treatment of ED. On separate days, the men underwent two exercise treadmill tests, which consisted of a six-minute walk and a maximal exercise test. About an hour before the first test, the men received either 50 milligrams of sildenafil or a placebo. On the second day, the men received the opposite treatment (sildenafil or placebo) before exercise.


Those treated with sildenafil had significantly lower blood pressure and heart rate and improvement in measures of oxygen consumption and carbon dioxide production

compared with those on placebo
. Total exercise time also increased significantly. A separate evaluation showed that treatment with sildenafil was associated with higher scores on a questionnaire related to erectile function.


I just dont know how you reached the conclusion that you did 'DAVAOENO', where you tried to be-little the Test Results, by suggesting anyone who exersises, will get better performance.

Have you ever talken a Treadmilll Stress Test 'DAVAOENO'.

Well after losing 20Kg in weight and had achieved that by going to a Gym at least 3 times a week for nearly 4 months, I would expect that had I repeated a Stress Test on a tread Mill, my results would have shown better performance.

BUT that is NOT the Topic of this THREAD. You completely issed the point that those taking Viagra got better performance than when taking Placebo, which suggests VIAGRA helps those with Cardiac Problems get better results without doing the Diet and the Exercise.

So what if you do all 3 - Diet, Exercise and Viagra (with Cardialogist approval)?

It is NOT for everyone, with or without Heart Condition (pulmonary hypertension)

If YOU had read http://circ.ahajourn...t/99/1/168.full


2. Cardiovascular Effects
a. Effects on Cardiac Contractility
Unlike cAMP-specific PDE3 inhibitors (milrinone, vesnarinone, and enoximone) that increase long-term mortality in patients with heart failure,17 19 sildenafil is highly selective (>4000-fold) for human PDE5 over human PDE3 and has not been found to elevate cAMP (Pfizer, unpublished data). The cardiotoxic effects of PDE3 inhibitors are thought to be related to increases in intracellular cAMP in the myocardium.15 19 20 Furthermore, PDE5 is not present in cardiac myocytes, and sildenafil has been shown to have no direct inotropic effects on dog trabeculae muscle (Pfizer, unpublished data). However, sildenafil has not been investigated extensively in heart failure patients.
b. Effects on Blood Pressure and Heart Rate
Sildenafil produces a transient modest reduction in systolic (8 to 10 mm Hg) and diastolic (5 to 6 mm Hg) blood pressures, with peak effects evident at 1 hour after the dose (coincident with peak plasma concentrations) and returning to baseline values by 4 hours after the dose (Pfizer, unpublished data). No significant effects are observed on heart rate. The hypotensive effects of sildenafil are neither age dependent (similar reductions in blood pressure in patients aged <65 years compared with those >65 years) nor dose related (over the range of 25 to 100 mg) and rarely result in reports of orthostatic effects. Doses as high as 800 mg have been well tolerated in some healthy volunteers.13
c. Effects on Central Hemodynamics and Peripheral Vasculature
In normal volunteers, no significant changes in cardiac index were evident up to 12 hours after the dose for oral sildenafil (100 to 200 mg) or intravenous sildenafil (20 to 80 mg) (Pfizer, unpublished data). Significant decreases in systemic vascular resistance index were reported at the end of intravenous sildenafil infusion (20 to 80 mg), when plasma concentrations were highest (Pfizer, unpublished data). Sildenafil has both arteriodilator and venodilator effects on the peripheral vasculature (Pfizer, unpublished data). In 8 patients with stable angina, intravenous sildenafil reduced systemic and pulmonary arterial pressures and cardiac output by 8%, 25%, and 7%, respectively, consistent with its mixed arterial (systemic and pulmonary hypotension) and venous (drop in stroke volume secondary to decreased preload) vasodilator effects.14
In conclusion, consistent with the anticipated effects resulting from an increase in cGMP levels in vascular smooth muscle, sildenafil possesses vasodilatory properties, which result in mild, generally clinically insignificant decreases in blood pressure when taken alone.


What does this mean?


In patients with known coronary artery disease whose antianginal medicines were stopped for study purposes,27 Drory et al compared the electrocardiographic monitoring findings in sexual activity with a near-maximal exercise treadmill test (ETT). Most patients had previous myocardial infarctions and were in New York Heart Association functional class I or II. ECG criteria for ischemia during intercourse were found in one third of the patients; two thirds of the time, this was silent rather than symptomatic ischemia. All patients with ischemia during coitus also demonstrated ischemia at ETT. Drory et al also noted significant variation in heart rate response to coitus, with an average heart rate of 118 bpm but with some patients attaining a heart rate of 185 bpm at orgasm. Other small studies with ECG monitoring during intercourse in patients with coronary artery disease concluded that sexual activity may provoke increased ventricular ectopic activity that is not necessarily elicited by other stimuli.28 Jackson29 found that in 19 patients with ischemic heart disease who developed angina during sexual intercourse, these symptoms were abolished with ß-blockade. The mean maximum heart rate during sexual intercourse with and without use of ß-blockers was 82 and 122 bpm, respectively. This would suggest that these patients may have different hemodynamics while taking antianginal medication that may afford them some protection or lower their risk of ischemia. It should be emphasized that coital death is rare, encompassing only 0.6% of sudden death cases.30 Muller et al31 found by retrospective case-crossover methodology that although sexual activity can trigger the onset of myocardial infarction, the relative risk in the 2 hours after sexual activity is very low (2.5; 95% CI, 1.7 to 3.7). Furthermore, sexual activity was a likely contributor to the onset of myocardial infarction only 0.9% of the time. Additionally, they found that the relative risk of myocardial infarction is not increased in patients with a prior history of cardiac disease and that regular exercise appears to prevent triggering. It should be cautioned that these reassuring data should not be extrapolated to patients taking sildenafil if they perform at higher cardiac and metabolic expenditures during coitus. The hemodynamic changes associated with sexual activity may be far greater with an unfamiliar than with a familiar partner, in unfamiliar settings, and after excessive eating and consumption of alcohol. The person most at risk is usually middle-aged and having extramarital relations.
The ETT can gauge the potential cardiac stress of sexual activity. If a patient can achieve 5 or 6 METS on the ETT without demonstrating arrhythmias or ischemia electrocardiographically, they most likely are not at high risk for developing myocardial ischemia as a result of their normal sexual activities.


So would taking VIAGRA be good or bad for me with a known Cardiac Problem?

No idea and I certainly would not go taking Viagra just to find out, without consultation with my Cardiologist (who conducted my Angiogram).


In fact I suggest anyone considering taking Viagra for any ED reason, consult a Doctor, as those with ED may also be liable to have Heart problems.

The likes of Viagra, Levitra, and Cialis—all work by the same means, and they have similar side effects. The most common are headaches and facial flushing, which occur in 15% of men. Other reactions include nasal congestion, indigestion, and back pain. These side effects are mild and temporary. The most important worry about ED pills is their ability to widen arteries enough to lower blood pressure. And men who are taking nitrates should never use any of the ED pills.



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